The introduction of the CUCKOO Workgroup. Also called as covalent modifications, are chemical modifying processes of proteins after their translation.

Although many studies have tried to dissect the regulato.

Nadolski and Linder, 2007. Although most of lipid modifications are irreversible, protein S-palmitoylation. Dietrich and Ungermann, 2004. El-Husseini Ael and Bredt, 2002.

Software was implemented in JAVA and could predict kinase-specific phosphorylation sites for 408. Recently, we released GPS 3.

During cell cycle, numerous proteins temporally and spatially localized in distinct sub-cellular regions including centrosome. Related or homolog structures in plants and budding yeast called as phragmoplast. And five animals, including. Then the integrated and searchable database M.

Have been developed to contain PTM information of proteins. However, these annotations are usually not integrated.

The Nobel Prize in Chemistry 2004 was award to Aaron Ciechanover, Avram Hershko and Irwin Rose for their discovery of ubiquitin-mediated protein degradation. Which could be targeted by pathogen-specific drugs. Furthermore, proteome-wide discoveries of pupylation targets i.

Tannenbaum and White, 2006. Although enzymatic mechanisms of protein. Nitrosylation were still elusive, several enzymes were proven to facilitate.

Seeler and Dejean, 2003.

This paper is the TOP TEN ACCESSED ARTICLES. Early after the discovery of the freely-diffusible signaling molecule and second messenger nitric oxide. Van der Vliet, A.